Disodium Glycyrrhizinate
Disodium Glycyrrhizinate is the di-sodium salt of glycyrrhizic acid, assigned CAS number 71277-79-7 and sold as a white to pale yellow crystalline powder.
Two of the three carboxyl groups of the glycyrrhizinate anion are neutralised with sodium, leaving the third protonated. The salt is widely used in Japan, where it is the dominant kanzo-derived sweetener and umami enhancer for soy sauce, miso, and pickled vegetables.
We source bulk Disodium Glycyrrhizinate from top China manufacturers for our partners. The manufacturer is in Qinghai. A smaller requirement can ship in a combined container with other ingredients.
Please send the grade you need, the volume and your destination port, and we will come back with a solution and a price.
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- Packaging
- 25 kg kraft paper bag with PE inner liner
- ISO 9001
- HACCP
- Halal
- Kosher
Specifications
| Item | Specification |
|---|---|
| Appearance | White to pale yellow crystalline powder |
| Identification (HPLC) | Conforms |
| Assay (HPLC, dry basis) | ≥ 95.0% |
| Sodium Content | 5.0% - 6.0% |
| Loss on Drying (105 °C, 3 h) | ≤ 8.0% |
| pH (1% aqueous solution) | 5.0 - 8.0 |
| Sulphated Ash | 14.0% - 18.0% |
| Residual Solvent (Ethanol) | ≤ 0.5% |
| Arsenic (as As) | ≤ 2 mg/kg |
| Heavy Metals (as Pb) | ≤ 10 mg/kg |
| Total Plate Count | ≤ 1,000 cfu/g |
| Yeast and Mould | ≤ 100 cfu/g |
| Salmonella | Negative/25g |
Common Markets Grades
Disodium Glycyrrhizinate is graded by HPLC assay at 90 percent, 95 percent, and 98 percent on a dry basis.
The 95 percent grade serves Japanese soy sauce, miso, and shoyu producers as the standard kanzo enhancer.
A 98 percent grade is preferred for clear beverages, mouthwashes, and pharmaceutical syrups where higher purity is needed to avoid colour drift.
Sodium content is tightly specified around 5 to 6 percent by mass, which corresponds to two sodium ions per glycyrrhizinate molecule. Sulfated ash, heavy metals, and residual solvents are all controlled to Japanese food additive standards.
Applications
- Japanese soy sauce and tamari as a sweetener and umami enhancer
- Miso paste and fermented soybean products
- Tsukemono and Japanese pickled vegetables
- Soju, shochu, and other Asian distilled spirits
- Salted fish products and dried seafood seasonings
- Instant noodles and seasoning powders
- Throat lozenges and herbal pastilles
- Mouthwashes and oral care formulations
- Pharmaceutical syrups and pediatric liquids
- Topical anti-inflammatory creams
- Functional supplements and herbal extracts
- Confectionery in licorice and anise flavour systems
Brands Using Disodium Glycyrrhizinate
Widely-distributed consumer products that list Disodium Glycyrrhizinate on the ingredient label.
Brand names, product names and logos are the property of their owners. They appear here as published evidence that the ingredient is used, taken from the brand's own label or website. Their appearance is not an endorsement, and it does not mean the brand buys from us or from any manufacturer listed on this site.
China Manufacturers of Disodium Glycyrrhizinate
Top Disodium Glycyrrhizinate manufacturers in China.
Company names and logos are the property of the manufacturers themselves. They are listed here because our own directory records them as producing this ingredient. A listing is not an endorsement by them, and we do not represent them or speak on their behalf.
How We Help Source Disodium Glycyrrhizinate
Direct Factory Sourcing
We run the whole process: selecting the manufacturer from the top Chinese food ingredient producers, negotiating the price, verifying quality, and coordinating the logistics. You deal with us instead of with several factories at once.
Original Packaging and Documents from the Manufacturer
The manufacturer sends your Disodium Glycyrrhizinate out of its own factory in the original packing, through to your destination port. The COA, COO, MSDS, TDS and any certifications reach you from the manufacturer as well.
Free Samples and Lead Time
We send 100 to 500 g free for your own laboratory to test and you cover only the courier, usually within 2 to 3 working days. ETD is usually within 7 to 15 days once the order is confirmed, and we check that date against the factory's own manufacturing schedule before we give it to you.
Combined Shipment
We can load Disodium Glycyrrhizinate together with other ingredients such as Stevia, Erythritol and Maltitol into one 20' FCL. If your quantity is small, we can also ship LCL.
Regulatory Status
Disodium Glycyrrhizinate is one of the most established licorice-derived additives in the Japanese food code, where glycyrrhizin salts are permitted as natural sweeteners and flavour enhancers across most categories.
In the European Union the substance falls under the same intake framework as other glycyrrhizinate salts, with EFSA opinions on glycyrrhizin reaffirming guidance to keep habitual intake below approximately 100 mg per day.
The United States Food and Drug Administration recognises licorice and its sodium derivatives as GRAS under 21 CFR 184.1408 at the use-level limits set for licorice extract.
Korean and Taiwanese food codes mirror the Japanese approach for soy sauce and fermented seasoning applications. Kosher and Halal certifications are routinely available.
Manufacturing Process
Disodium Glycyrrhizinate is prepared by partial neutralisation of glycyrrhizic acid with two molar equivalents of sodium hydroxide or sodium carbonate.
Free glycyrrhizic acid is first isolated from a hot-water licorice extract by sulphuric acid precipitation, washed, and recrystallised. The purified acid is then suspended in water and the alkali is dosed slowly until the pH stabilises around 6.5 to 7.0, the endpoint that corresponds to the di-salt.
The solution is decolorised with activated carbon, polish-filtered, concentrated under vacuum, and finally spray-dried.
Final lots are tested by HPLC for assay, by flame atomic absorption for sodium content, and by pharmacopoeial methods for heavy metals, residual solvents, and microbiological purity.
