Copper Bisglycinate
Copper Bisglycinate is a chelate of copper with two molecules of the amino acid glycine. It has the formula Cu(C2H4NO2)2 and CAS number 13479-54-4. The compound contains approximately 24 percent elemental copper.
The chelate is a fine blue powder of moderate water solubility. Its bonded structure shields the copper ion from binding with dietary phytate, polyphenols, and competing minerals in the gut, supporting the highest bioavailability tier among commercial copper forms.
We source bulk Copper Bisglycinate from top China manufacturers for our partners. The manufacturer is in Hebei. A smaller requirement can ship in a combined container with other ingredients.
Please send the grade you need, the volume and your destination port, and we will come back with a solution and a price.
or call +86-21-6858 0751
- Packaging
- 25 kg kraft paper bag with PE inner liner
- ISO 9001
- HACCP
- Halal
- Kosher
Specifications
| Item | Specification |
|---|---|
| Appearance | Light blue to blue-green powder |
| Assay | ≥ 98.0% |
| Copper Content | 20.0–25.0% |
| Glycine Content | ≥ 45.0% |
| Loss on Drying | ≤ 2.0% |
| Lead | ≤ 2 ppm |
| Total Plate Count | ≤ 1000 CFU/g |
| Assay/Purity | ≥98% |
| Moisture | ≤5% |
| pH | 6.0-8.0 |
| Heavy Metals | ≤10 ppm |
| Arsenic | ≤1 ppm |
| Residue on Ignition | ≤0.5% |
| Yeast & Mold | ≤100 cfu/g |
| E.Coli | Negative |
| Salmonella | Negative |
Common Markets Grades
Copper Bisglycinate serves nutrition channels as a chelated copper source.
Fully reacted bisglycinate grade carries two glycine ligands per Cu(II) centre. Chelation is verified by infrared spectroscopy, which shows the disappearance of the free glycine carboxyl stretch and the appearance of the metal-bonded carboxylate band.
Pharmaceutical and supplement grade is graded at 18 to 24 percent elemental copper depending on water content. Heavy metal limits are aligned with ICH Q3D Option 2A for oral supplements.
Infant nutrition grade is produced with tight microbiological limits, low residual solvents, and full traceability of glycine origin.
Spray-dried agglomerated grade is produced for direct-compression tablets and capsule blending. Fine powder grade is preferred for liquid suspensions and powder beverage mixes.
Fermentation-derived glycine is increasingly used to support vegan and non-GMO labelling. Animal-source glycine is still permitted in many supplement channels.
Applications
- Premium adult multivitamin and multimineral tablets and capsules
- Prenatal and pediatric multivitamins where bioavailability matters
- Standalone copper supplement formats
- Infant formula and follow-on formula mineral premixes
- Clinical nutrition products for medical and post-surgical recovery
- Beauty-from-within supplements targeting hair pigmentation and connective tissue
- Functional beverages and powdered drink mixes
- Effervescent immune-support tablets paired with zinc bisglycinate
- Sports nutrition recovery formulas
- Premium pet food and companion-animal supplements
- Aquaculture feed for high-value species
Brands Using Copper Bisglycinate
Widely-distributed consumer products that list Copper Bisglycinate on the ingredient label.
- NOW FoodsCopper Glycinate 3 mg Tablets (Albion Copper Bisglycinate) ↗Tablets using Albion-patented copper bisglycinate chelate at 3 mg copper each.Label verified 2026-05-24
- SolgarChelated Copper 2.5 mg Tablets (Copper Bisglycinate) ↗Solgar Chelated Copper provides 2.5 mg of patented bioavailable copper bisglycinate (copper glycinate amino acid chelate) per vegetarian tablet for collagen, connective tissue and trace-mineral support.Label verified 2026-05-24
- Pure EncapsulationsCopper (glycinate) 2 mg Capsules ↗Pure Encapsulations Copper (glycinate) supplies 2 mg of copper as copper bisglycinate chelate per vegetarian capsule for red-blood-cell formation, iron absorption and energy metabolism.Label verified 2026-05-24
Brand names, product names and logos are the property of their owners. They appear here as published evidence that the ingredient is used, taken from the brand's own label or website. Their appearance is not an endorsement, and it does not mean the brand buys from us or from any manufacturer listed on this site.
China Manufacturers of Copper Bisglycinate
Top Copper Bisglycinate manufacturers in China.
Company names and logos are the property of the manufacturers themselves. They are listed here because our own directory records them as producing this ingredient. A listing is not an endorsement by them, and we do not represent them or speak on their behalf.
How We Help Source Copper Bisglycinate
Direct Factory Sourcing
We run the whole process: selecting the manufacturer from the top Chinese food ingredient producers, negotiating the price, verifying quality, and coordinating the logistics. You deal with us instead of with several factories at once.
Original Packaging and Documents from the Manufacturer
The manufacturer sends your Copper Bisglycinate out of its own factory in the original packing, through to your destination port. The COA, COO, MSDS, TDS and any certifications reach you from the manufacturer as well.
Free Samples and Lead Time
We send 100 to 500 g free for your own laboratory to test and you cover only the courier, usually within 2 to 3 working days. ETD is usually within 7 to 15 days once the order is confirmed, and we check that date against the factory's own manufacturing schedule before we give it to you.
Combined Shipment
We can load Copper Bisglycinate together with other ingredients such as Sodium Acetate, Calcium Citrate and Sodium Lactate into one 20' FCL. If your quantity is small, we can also ship LCL.
Regulatory Status
Copper Bisglycinate is approved as a nutrient source across major global markets.
The European Union authorises Copper Bisglycinate as a source of copper for food supplements under Annex II of Directive 2002/46/EC and for fortified foods under Regulation (EC) No 1925/2006. The compound was added to the permitted list following a positive EFSA scientific opinion on its safety and bioavailability.
The U.S. Food and Drug Administration recognises amino acid chelates of copper, including copper bisglycinate, as suitable for use in dietary supplements under the general framework for nutrient sources.
EFSA scientific opinion (EFSA Journal 2009;7(11):1383) concluded that copper bisglycinate is bioavailable and safe at intended use levels in food supplements.
For use in infant formula, copper compounds including the bisglycinate are evaluated case by case against Regulation (EU) 2016/127. Halal, Kosher, vegan, and non-GMO certifications exist when the glycine source qualifies.
Manufacturing Process
Copper Bisglycinate is manufactured by direct chelation of copper ions with glycine in aqueous solution.
Glycine is dissolved in deionized water at 50 to 70 degrees Celsius to form a 10 to 20 percent solution. Copper carbonate (basic) or freshly precipitated copper hydroxide is added in two-to-one molar ratio of glycine to copper.
The reaction is held with gentle agitation for 1 to 3 hours under mild heat. The pH stabilises in the 6.5 to 7.5 region as the glycine carboxyl groups deprotonate and the amine nitrogen and carboxyl oxygen form coordinate bonds with the copper centre. The mixture turns from pale slurry to a deep blue solution as the chelate forms.
Infrared spectroscopy is used inline or on samples to confirm chelation. The clear blue solution is filtered to remove any unreacted copper source, concentrated under vacuum, and spray-dried or allowed to crystallise on cooling.
The dried product is milled and tested by ICP-MS for heavy metals and by infrared spectroscopy for chelation degree. Each batch is also tested for free glycine, residual copper carbonate, and microbiological compliance.
