Zinc Bisglycinate
Zinc bisglycinate is a zinc amino acid chelate in which a zinc ion is held by two glycine molecules, each binding through its amino nitrogen and a carboxyl oxygen to form two stable five membered rings around the metal.
The material is a white to off white free flowing powder. Fully reacted anhydrous chelate has a theoretical zinc content near thirty percent, and commercial grades are declared between about twenty and thirty percent depending on hydration and on whether free glycine has been left in the product as a buffer. Formulators dose on the declared elemental zinc figure rather than on the chelate assay.
Solubility in water is modest at neutral pH and increases in acid conditions, so the powder disperses in dry blends and premixes without dissolving and passes into solution in the stomach. The chelate is less astringent and less metallic in taste than zinc sulphate, which matters in chewables and powders, and it interacts less aggressively with vitamins in a premix, giving better vitamin C and vitamin A retention over shelf life.
We source bulk Zinc Bisglycinate from top China manufacturers for our partners. The manufacturers are in Hebei. A smaller requirement can ship in a combined container with other ingredients.
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- Function
- Amino acid
Specifications
| Item | Specification |
|---|---|
| Appearance | White to off-white free flowing powder |
| Identification | Conforms by infrared spectrum and zinc ion test |
| Zinc (elemental) | Meets declared content, typically 20.0 to 30.0% |
| Glycine to zinc molar ratio | 1.8 to 2.2 to 1 |
| Free glycine | Not more than 5.0% |
| Loss on drying | Not more than 5.0% |
| Sulphated ash | Not more than 2.0% |
| pH (1% aqueous suspension) | 6.0 to 8.0 |
| Particle size | Not less than 95% through 80 mesh |
| Lead | Not more than 2.0 mg/kg |
| Arsenic | Not more than 1.5 mg/kg |
| Cadmium | Not more than 1.0 mg/kg |
| Mercury | Not more than 0.1 mg/kg |
| Total plate count | Not more than 1,000 cfu/g |
Common Markets Grades
Food and supplement grade is the main tier, made to a controlled two to one glycine to zinc ratio, declared on elemental zinc, and tested for heavy metals and microbiology for use in tablets, capsules, powders and fortified foods. Feed grade chelate is the higher volume product, specified on guaranteed zinc content for trace mineral premixes and complete feeds.
Within the food tier, the practical choices are assay and physical form. High assay grades close to the stoichiometric zinc limit are used where dose volume is limited, and buffered grades carrying additional free glycine are preferred where a lower, easier to blend assay suits the premix. A fine powder passing 80 mesh serves capsule filling and beverage dispersions, while granulated grades with improved flow and reduced dusting are used for direct compression tabletting and for feed premix handling.
Applications
- Zinc supplement tablets and capsules, chosen over the sulphate for its milder taste and lower stomach irritation
- Immune support formulas combining zinc with vitamin C, vitamin D and elderberry
- Multivitamin and multimineral premixes, where the chelate is less reactive towards oxidation sensitive vitamins
- Chewable tablets, gummies and children's supplements where the metallic taste of inorganic zinc is unacceptable
- Prenatal and women's health supplements as the zinc carrier in a mineral heavy formula
- Skin, hair and nail products, where zinc is included alongside biotin and collagen peptides
- Fortified powdered beverages, meal replacements and nutrition bars
- Poultry, swine and aquaculture feeds, where the chelated form limits interaction with dietary phytate
- Companion animal supplements and complete pet foods within the trace element pack
Brands Using Zinc Bisglycinate
Widely-distributed consumer products that list Zinc Bisglycinate on the ingredient label.
- NutricostNutricost Zinc Bisglycinate ↗A single ingredient vegan capsule delivering 50 mg of zinc bisglycinate per serving.Label verified 2026-08-31
- CodeageMen's Daily Probiotic ↗A 50 billion CFU probiotic capsule that also contains zinc bisglycinate chelate and saw palmetto extract.Label verified 2026-08-31
- CodeageGut Muscle Formula ↗A chocolate brownie flavoured gut and muscle powder combining Bacillus coagulans at 2 billion CFU with zinc bisglycinate.Label verified 2026-08-31
Brand names, product names and logos are the property of their owners. They appear here as published evidence that the ingredient is used, taken from the brand's own label or website. Their appearance is not an endorsement, and it does not mean the brand buys from us or from any manufacturer listed on this site.
China Manufacturers of Zinc Bisglycinate
Top Zinc Bisglycinate manufacturers in China.
Hebei LiWellso Biotech Co.,Limited11 ingredients in the directory
Shijiazhuang Donghua Jinlong Chemical Co., Ltd.9 ingredients in the directory
Company names and logos are the property of the manufacturers themselves. They are listed here because our own directory records them as producing this ingredient. A listing is not an endorsement by them, and we do not represent them or speak on their behalf.
Regulatory Status
In the United States zinc bisglycinate is used as a dietary ingredient in supplements manufactured under 21 CFR Part 111, and the chelate has also been the subject of a GRAS notification supporting defined uses in conventional foods and beverages, alongside the long established zinc sources such as zinc sulphate, oxide and gluconate that 21 CFR Part 182 lists as generally recognised as safe. For animal feed, zinc amino acid chelates are covered by the Association of American Feed Control Officials ingredient definitions.
In the European Union the annex to Directive 2002/46/EC sets out the zinc forms permitted in food supplements, and Regulation 1925/2006 sets out those permitted for the fortification of foods, both of which have been amended over time to add amino acid chelate forms following EFSA opinions, so formulators confirm the current listing for the exact chelate before use. Zinc chelate of glycine hydrate is separately authorised as a nutritional feed additive in the EU feed additive register with its own purity conditions. Codex addresses zinc through the advisory lists of nutrient compounds attached to its infant formula and special dietary use standards.
Manufacturing Process
The chelate is formed by reacting a zinc source with glycine in water. Zinc oxide or zinc carbonate is slurried with two molar equivalents of glycine and heated with agitation; the reaction is driven by consumption of the basic zinc compound and, in the carbonate case, by the escape of carbon dioxide. Using the oxide or carbonate rather than the sulphate avoids leaving a mineral anion in the product, which would otherwise have to be washed out and would show up in the sulphated ash result.
The mixture is held at controlled temperature and pH until chelation is complete, verified by the fall in free glycine and by infrared confirmation of the chelate bond. Unreacted zinc solids are removed by filtration, and the liquor is concentrated and dried, most often by spray drying, which gives a rounded, free flowing particle. Where a denser particle is wanted the wet cake is dried in a fluid bed instead. The dried solid is milled, sieved, passed over magnets and through a metal detector, then blended to the declared zinc content and packed.
