CAS 489-32-7

Epimedium Extract

Epimedium Extract is a concentrated preparation of the aerial parts of various Epimedium species, a genus of low perennial herbs known in English as horny goat weed and in Chinese as yin yang huo.

The extract is standardised to icariin, the principal prenylated flavonoid of the genus, with related flavonoids epimedin A, B, and C contributing to the full fingerprint.

We source bulk Epimedium Extract from top China manufacturers for our partners. The manufacturers are in Jilin and Shaanxi. For this ingredient the minimum order is 50 kg, and a smaller requirement can ship in a combined container with other ingredients.

Please send the grade you need, the volume and your destination port, and we will come back with a solution and a price.

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Epimedium Extract
Minimum order
50 kg
Packaging
25 kg fibre drum with double PE liner
  • ISO 9001
  • HACCP
  • Halal
  • Kosher

Specifications

ItemSpecification
AppearanceLight brown to dark brown free-flowing powder
Icariin content (HPLC)10% / 20% / 60% / 98% (grade dependent)
Total flavonoids≥ 30% (10% icariin grade)
Loss on drying≤ 5.0%
Residue on ignition≤ 5.0%
Heavy metals (as Pb)≤ 2 mg/kg
Total plate count≤ 1000 cfu/g
SourceEpimedium leaves (E. brevicornum, E. sagittatum, others)

Common Markets Grades

Epimedium Extract is graded by icariin content as measured by HPLC against a reference standard.

Standard commercial grades include 5, 10, 20, 30, 40, 50, and 60 percent icariin. The 10 and 20 percent grades are the most widely used in capsule and tablet formulations.

Higher-potency grades at 80 to 98 percent icariin are produced by macroporous resin enrichment and recrystallisation, primarily for clinical material and as a starting point for icariin derivatives.

Total flavonoid grades are specified separately, typically at 20 to 40 percent total flavonoids including epimedin A, B, C and icariin.

Botanical source is part of the specification. Epimedium brevicornu, E. sagittatum, E. pubescens, E. wushanense, and E. koreanum are the five species accepted in the China Pharmacopoeia, each with a characteristic flavonoid ratio.

Applications

  • Men's health capsules and tablets positioned for vitality and stamina
  • Pre-workout and testosterone-support blends in sports nutrition
  • Bone health supplements paired with calcium, vitamin D3, and vitamin K2
  • Joint and mobility formulations for the active mature consumer
  • Traditional Chinese medicine compound formulas requiring yin yang huo
  • Couples-positioned wellness products in capsule and gummy formats
  • Liquid tonics, herbal wines, and tincture blends in the Asian functional drink market
  • Functional coffees and pre-workout drinks targeting a vitality claim
  • Postmenopausal support formulas focused on bone density
  • Adaptogen and longevity stacks paired with cordyceps or reishi
  • Hair regrowth and scalp tonics in the traditional medicine and modern cosmetic categories
  • Topical creams and serums claiming firming and circulation-support activity

China Manufacturers of Epimedium Extract

Top Epimedium Extract manufacturers in China.

Company names and logos are the property of the manufacturers themselves. They are listed here because our own directory records them as producing this ingredient. A listing is not an endorsement by them, and we do not represent them or speak on their behalf.

How We Help Source Epimedium Extract

  • Direct Factory Sourcing

    We run the whole process: selecting the manufacturer from the top Chinese food ingredient producers, negotiating the price, verifying quality, and coordinating the logistics. You deal with us instead of with several factories at once.

  • Original Packaging and Documents from the Manufacturer

    The manufacturer sends your Epimedium Extract out of its own factory in the original packing, through to your destination port. The COA, COO, MSDS, TDS and any certifications reach you from the manufacturer as well.

  • Free Samples and Lead Time

    We send 100 to 500 g free for your own laboratory to test and you cover only the courier, usually within 2 to 3 working days. ETD is usually within 7 to 15 days once the order is confirmed, and we check that date against the factory's own manufacturing schedule before we give it to you.

  • Combined Shipment

    We can load Epimedium Extract together with other ingredients such as Astaxanthin, Dehydrated Garlic and Lutein into one 20' FCL. If your quantity is small, we can also ship LCL.

Regulatory Status

Epimedium is regulated as a dietary ingredient under DSHEA in the United States. The U.S. FDA has not issued species-specific approvals; suppliers maintain identity controls to confirm one of the pharmacopoeia-accepted species.

Health Canada lists Epimedium species in its Natural Health Products Ingredients Database with monographs covering traditional Chinese medicine use.

The China Pharmacopoeia carries a monograph for yin yang huo that accepts five species and specifies minimum icariin content of 0.5 percent in the dried herb.

The European Medicines Agency has not issued a herbal monograph for Epimedium. Use in EU member states varies, with some countries permitting it as a food supplement and others requiring case-by-case assessment.

Kosher and Halal certifications exist where extraction solvents and carrier systems contain no animal-derived components.

Manufacturing Process

The aerial parts (leaves and stems) are harvested in summer after flowering, when icariin content peaks. The major production regions are Shaanxi, Sichuan, Gansu, and Hubei provinces in China.

Harvested material is air-dried in shade, sorted to remove woody stems and foreign matter, and milled to a coarse powder.

Extraction uses ethanol-water mixtures at 50 to 70 percent ethanol with multi-stage countercurrent reflux. The miscella is filtered and concentrated under vacuum.

For standard flavonoid grades the concentrate is spray-dried directly with a carrier. For higher-potency grades it is loaded onto a macroporous adsorption resin (D101, AB-8, or HPD-100 are typical), washed to remove sugars and pigments, then eluted with ethanol of increasing concentration to recover the flavonoid fraction.

Some producers offer enzymatically processed or fermented Epimedium extract, in which beta-glucosidase converts icariin to icariside II or icaritin. These derivatives are produced separately, often at higher prices, and are distinguished by HPLC profile.