Monoammonium Glycyrrhizinate
Monoammonium Glycyrrhizinate is the singly-protonated ammonium salt of glycyrrhizic acid, assigned CAS number 53956-04-0 and sold as a yellowish crystalline powder.
Compared with the tri-salt, the mono-salt carries a single ammonium counter-ion balancing one of the three carboxylate groups of the glycyrrhizinate anion, leaving the other two protonated. This raises its acidity and reduces aqueous solubility, which suits applications where slow release of sweetness is desired.
We source bulk Monoammonium Glycyrrhizinate from top China manufacturers for our partners, working with several of them. The manufacturers are in Gansu, Shaanxi and Jiangsu. A smaller requirement can ship in a combined container with other ingredients.
Please send the grade you need, the volume and your destination port, and we will come back with a solution and a price.
or call +86-21-6858 0751
- Packaging
- 25 kg kraft paper bag with PE inner liner
- ISO 9001
- HACCP
- Halal
- Kosher
Specifications
Grades / Types Available: Cosmetic grade
| Item | Specification |
|---|---|
| Appearance | White to pale yellow crystalline powder |
| Assay (as Glycyrrhizic Acid) | ≥ 73.0% |
| Loss on Drying | ≤ 8.0% |
| pH (1% solution) | 5.5–7.5 |
| Residue on Ignition | ≤ 0.5% |
| Heavy Metals (as Pb) | ≤ 10 ppm |
| Total Plate Count | ≤ 1000 CFU/g |
| Solubility | Dissolved in ethanol, 1,3-butanediol. Do not dissolve in water |
| Typical Dosage | 1‰-5‰ |
| Packing | 1kg aluminum foil bag |
| Transport | Non-hazardous cargo(IMO/IATA) |
Common Markets Grades
Monoammonium Glycyrrhizinate is graded by HPLC assay, most commonly at 95 percent and 98 percent purity on a dry basis.
The food grade serves licorice confectionery, throat lozenges, and herbal tea blends where its slower dissolution gives a longer-lingering sweet note.
A higher-purity pharmacopoeial grade is used in cough syrups, oral care, and topical formulations.
Moisture typically runs below 5 percent and sulfated ash below 0.5 percent. Buyers choose between fine and granular particle size cuts, depending on whether the material is dry blended or dispersed in water.
Applications
- Hard candy and toffee where slow-release sweetness extends the licorice note
- Throat lozenges and herbal pastilles
- Chewing gum and breath mints in licorice and anise flavours
- Herbal teas and traditional decoctions
- Cough syrups and pediatric pharmaceutical liquids
- Topical anti-inflammatory creams and lotions
- Tobacco casing and snuff sweetening
- Salty licorice and salmiak confections
- Functional supplements positioned for respiratory and adrenal support
- Toothpaste and mouthwash formulations
- Soy sauce and miso for sweetness in fermented sauces
- Dark beer and stout for licorice character
Brands Using Monoammonium Glycyrrhizinate
Widely-distributed consumer products that list Monoammonium Glycyrrhizinate on the ingredient label.
Brand names, product names and logos are the property of their owners. They appear here as published evidence that the ingredient is used, taken from the brand's own label or website. Their appearance is not an endorsement, and it does not mean the brand buys from us or from any manufacturer listed on this site.
China Manufacturers of Monoammonium Glycyrrhizinate
Top Monoammonium Glycyrrhizinate manufacturers in China.
- Gansu Sandi Plant Chemistry Co., Ltd.3 ingredients in the directory
Shaanxi Huatai Biological Fine Chemical Co., Ltd.5 ingredients in the directory
Zhangjiagang Free Trade Zone Hongyufeng Bio-Technology Co., Ltd.11 ingredients in the directory
Company names and logos are the property of the manufacturers themselves. They are listed here because our own directory records them as producing this ingredient. A listing is not an endorsement by them, and we do not represent them or speak on their behalf.
How We Help Source Monoammonium Glycyrrhizinate
Direct Factory Sourcing
We run the whole process: selecting the manufacturer from the top Chinese food ingredient producers, negotiating the price, verifying quality, and coordinating the logistics. You deal with us instead of with several factories at once.
Original Packaging and Documents from the Manufacturer
The manufacturer sends your Monoammonium Glycyrrhizinate out of its own factory in the original packing, through to your destination port. The COA, COO, MSDS, TDS and any certifications reach you from the manufacturer as well.
Free Samples and Lead Time
We send 100 to 500 g free for your own laboratory to test and you cover only the courier, usually within 2 to 3 working days. ETD is usually within 7 to 15 days once the order is confirmed, and we check that date against the factory's own manufacturing schedule before we give it to you.
Combined Shipment
We can load Monoammonium Glycyrrhizinate together with other ingredients such as Stevia, Erythritol and Maltitol into one 20' FCL. If your quantity is small, we can also ship LCL.
Regulatory Status
Monoammonium Glycyrrhizinate falls under the same regulatory framework as other glycyrrhizinate salts. In the European Union it is covered by the food additive code E958 as an ammonium salt of glycyrrhizic acid.
The United States Food and Drug Administration treats it as GRAS under 21 CFR 184.1408 (licorice and its derivatives), with the same use-level limits and the same consumer guidance to keep glycyrrhizin intake below roughly 100 mg per day to avoid pseudoaldosteronism.
EFSA opinions on glycyrrhizin from 2024 apply equally to mono- and tri-ammonium forms, since they release the same glycyrrhizinate anion in solution.
Japan permits the salt as a natural sweetener and flavour enhancer. Kosher and Halal certifications exist from licorice extract producers.
Manufacturing Process
Monoammonium Glycyrrhizinate is prepared by acidifying a hot-water licorice extract with sulphuric acid to precipitate free glycyrrhizic acid.
The crude acid is washed and redissolved in a controlled stoichiometric amount of aqueous ammonia, just enough to neutralise one of the three carboxyl groups. Maintaining the correct molar ratio is the central step that distinguishes the mono-salt from the tri-salt.
The solution is decolorised with activated carbon, polished by filtration, and then either spray-dried or recrystallised from aqueous ethanol.
Final material is milled to the desired particle size and tested by HPLC, with separate checks for free ammonia, residual sulphate, and heavy metals.
