CAS 90471-79-7

L-Carnitine Fumarate

L-Carnitine Fumarate is a 1:1 molecular salt of L-carnitine and fumaric acid that combines two metabolites of mitochondrial energy production in a single dry powder. It is positioned for cardiovascular and energy applications where the fumarate counter-ion is presented as a Krebs-cycle intermediate rather than a passive carrier.

The salt is a white crystalline powder with CAS 90471-79-7. L-Carnitine content is approximately 58 to 59 percent by weight, with fumaric acid balancing the remainder.

We source bulk L-Carnitine Fumarate from top China manufacturers for our partners. The manufacturers are in Liaoning. A smaller requirement can ship in a combined container with other ingredients.

Please send the grade you need, the volume and your destination port, and we will come back with a solution and a price.

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Packaging: 25 kg kraft paper bag with PE inner liner

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HACCP
Halal
Kosher

Specifications

Item	Specification
Appearance	White crystals or white crystalline powder
Assay	≥ 98.0%
Specific rotation	−16.5° to −18.5°
L-Carnitine content	58.5% ± 2.0%
Fumaric acid content	41.5% ± 2.0%
pH (1% solution)	3.0 to 4.0
Loss on drying	≤ 0.5%
Residue on ignition	≤ 0.5%
Heavy metals (as Pb)	≤ 10 mg/kg
Arsenic	≤ 1 mg/kg

Common Markets Grades

L-Carnitine Fumarate is produced primarily in food-supplement quality.

Standard supplement grade assays at 98.0 to 102.0 percent on the dried basis, with L-carnitine content controlled to 57.0 to 60.0 percent and fumaric acid measured by HPLC. D-carnitine, related substances, residual solvents, and heavy metals are restricted to tight in-house limits.

Particle size is generally a fine to medium powder. The salt flows reasonably well and shows better moisture resistance than the free base, though it is slightly more hygroscopic than the L-tartrate at high humidity.

The fumarate tastes mildly sour and is compatible with citrus, berry, and stone-fruit flavour systems in chewable and stick-pack formats.

Applications

Cardiovascular-support supplements alongside coenzyme Q10 and taurine
Sports-nutrition powders with an energy-metabolism story
Stick-pack hydration and endurance products
Capsule and tablet supplements for senior cardiovascular lines
Pre-workout blends in chewable formats
Liver-support and detoxification formulations
Functional shots and small-volume energy drinks
Heart-health combinations with magnesium and B-vitamins
Multivitamin sports premixes
Pet supplements for cardiac support in senior dogs
Equine cardiac and recovery formulations
Senior-nutrition fortified powders

Brands Using L-Carnitine Fumarate

Widely-distributed consumer products that list L-Carnitine Fumarate on the ingredient label.

Brand names, product names and logos are the property of their owners. They appear here as published evidence that the ingredient is used, taken from the brand's own label or website. Their appearance is not an endorsement, and it does not mean the brand buys from us or from any manufacturer listed on this site.

China Manufacturers of L-Carnitine Fumarate

Top L-Carnitine Fumarate manufacturers in China.

Company names and logos are the property of the manufacturers themselves. They are listed here because our own directory records them as producing this ingredient. A listing is not an endorsement by them, and we do not represent them or speak on their behalf.

How We Help Source L-Carnitine Fumarate

Direct Factory Sourcing
We run the whole process: selecting the manufacturer from the top Chinese food ingredient producers, negotiating the price, verifying quality, and coordinating the logistics. You deal with us instead of with several factories at once.
Original Packaging and Documents from the Manufacturer
The manufacturer sends your L-Carnitine Fumarate out of its own factory in the original packing, through to your destination port. The COA, COO, MSDS, TDS and any certifications reach you from the manufacturer as well.
Free Samples and Lead Time
We send 100 to 500 g free for your own laboratory to test and you cover only the courier, usually within 2 to 3 working days. ETD is usually within 7 to 15 days once the order is confirmed, and we check that date against the factory's own manufacturing schedule before we give it to you.
Combined Shipment
We can load L-Carnitine Fumarate together with other ingredients such as Glycine, L-Arginine and L-Leucine into one 20' FCL. If your quantity is small, we can also ship LCL.

Regulatory Status

L-Carnitine Fumarate is permitted in food supplements in the European Union under the Food Supplements Directive (2002/46/EC) Annex II as a recognised source of L-carnitine.

In the United States it is sold as a dietary ingredient under DSHEA. Fumaric acid as the counter-ion is itself a widely used food acidulant with long-standing GRAS status, which simplifies the regulatory positioning of the salt.

The salt has been included in EFSA evaluations of L-carnitine sources for food supplements with no separate safety concern raised on the fumarate counter-ion at normal use levels.

Halal and Kosher certifications are routinely available. Pharmacopoeial control is generally through USP and Ph. Eur. methodology for the L-carnitine moiety, supplemented by HPLC for fumarate content.

Manufacturing Process

L-Carnitine Fumarate Manufacturing Process

Loading process diagram…

L-Carnitine Fumarate is produced by neutralisation of L-carnitine free base with fumaric acid in aqueous or aqueous-alcohol medium, followed by crystallisation.

The L-carnitine starting material is sourced from the asymmetric synthesis route from epichlorohydrin or from biocatalytic routes operated by Chinese manufacturers. Fumaric acid is a standard commodity organic acid produced industrially by isomerisation of maleic acid.

The reaction is run with controlled stoichiometry to deliver the 1:1 salt and to avoid free fumaric acid contamination, which would cake the final powder. Crystallisation is followed by alcohol wash, vacuum drying, and milling.

Final product is checked for fumarate content, chiral purity, residual moisture, and microbiological quality before release.