Zinc Gluconate
Zinc Gluconate is the zinc salt of D-gluconic acid, with the empirical formula Zn(C6H11O7)2 and CAS number 4468-02-4. It contains approximately 14.3 percent elemental zinc.
The compound is a white to off-white crystalline powder that dissolves readily in water. Its gentle taste and superior gastrointestinal tolerance versus inorganic zinc salts have made it the default zinc carrier in cold-relief lozenges and consumer multivitamins.
We source bulk Zinc Gluconate from top China manufacturers for our partners, working with several of them. The manufacturers are mostly in Zhejiang, Shandong and Liaoning. A smaller requirement can ship in a combined container with other ingredients.
Please send the grade you need, the volume and your destination port, and we will come back with a solution and a price.
or call +86-21-6858 0751

- Packaging
- 25 kg kraft paper bag with PE inner liner
- ISO 9001
- HACCP
- Halal
- Kosher
Specifications
Grades / Types Available: Food Grade
| Item | Specification |
|---|---|
| Appearance | White crystalline powder |
| Assay | 97.0–102.0% |
| Zinc Content | 13.4–14.0% |
| Loss on Drying | ≤11.6% |
| Reducing Substances | ≤1.0% |
| Chloride | ≤0.05% |
| Sulphate | ≤0.05% |
| Lead | ≤3 mg/kg |
| Arsenic | ≤3 mg/kg |
| Cadmium | ≤3 mg/kg |
| Heavy Metals | ≤20 mg/kg |
| Solubility | Freely soluble in water |
| Purity | ≥98.0% |
| pH (1% Solution) | 5.0–7.0 |
| Shelf Life | 2 years |
| Storage Conditions | Cool, dry place, sealed packaging. |
| Size | 50-80mesh |
| EINECS | 206-076-3 |
| Formula | C12H22O14Zn |
| Brand | Fuxing |
Common Markets Grades
Zinc Gluconate is produced almost exclusively at pharmaceutical-grade purity.
USP and Ph. Eur. monograph material runs 97.0 to 102.0 percent assay calculated on the dried basis. Particle size is typically classified into fine powder for direct compression and granular grade for blending in pre-mixes.
Food grade conforms to FCC and JECFA specifications and is produced at the same assay window with controls on lead, arsenic, and reducing substances.
Lozenge-specific grades exist in spray-dried or roller-compacted form to improve flow and minimise the astringent metallic mouthfeel during slow oral dissolution.
Some suppliers also offer zinc gluconate in pre-blended functional premixes (with vitamin C, vitamin D3, or elderberry extract) for direct contract manufacturing of immune-support formats.
Applications
- Oral zinc supplement tablets, capsules, and softgels
- Multivitamin and multimineral formulations
- Cold-relief lozenges and throat sprays, often combined with vitamin C and elderberry
- Effervescent immune-support tablets
- Liquid pediatric supplements and oral drops
- Food fortification in functional beverages, nutrition bars, and meal replacements
- Medical nutrition products for wound healing and post-surgical recovery
- Topical acne lotions and dermatological creams
- Mouthwash and oral-care rinses for breath control
- Animal nutrition in companion-animal supplements and equine premixes
- Cosmetic formulations targeting sebum control and barrier support
Brands Using Zinc Gluconate
Widely-distributed consumer products that list Zinc Gluconate on the ingredient label.
- Cold-EEZE (ProPhase Labs)Cold Shortening Natural Cherry Lozenges (Zinc Gluconate) ↗Each lozenge contains zinc gluconate 2X HPUS (2.3%), delivering 13.3 mg zinc.Label verified 2026-05-24
- Cold-EEZE (ProPhase Labs)Cold Shortening Sugar Free Lozenges (Zinc Gluconate) ↗Cold-EEZE Sugar Free Lozenges use Zinc Gluconate 2X HPUS as the homeopathic active ingredient (13.3 mg zinc per lozenge) for shortening the common cold.Label verified 2026-05-24
- Nature Made (Pharmavite)Nature Made Zinc 30 mg Tablets (as Zinc Gluconate) ↗Nature Made Zinc 30 mg lists Zinc Gluconate as its source of 30 mg elemental zinc per tablet for immune support, USP Verified for ingredient and potency.Label verified 2026-05-24
- NOW FoodsNOW Zinc 50 mg Tablets (Zinc Gluconate) ↗Vegetarian tablets supplying 50 mg elemental zinc as zinc gluconate.Label verified 2026-05-24
Brand names, product names and logos are the property of their owners. They appear here as published evidence that the ingredient is used, taken from the brand's own label or website. Their appearance is not an endorsement, and it does not mean the brand buys from us or from any manufacturer listed on this site.
China Manufacturers of Zinc Gluconate
Top Zinc Gluconate manufacturers in China.
- Liao Yang Teng Yuan Food Additive Factory6 ingredients in the directory
Ningbo Hengxian Biotechnology Co., Ltd.1 ingredient in the directory
Penglai Marine (Shandong) Co., Ltd.10 ingredients in the directory
Shandong Xinhong Pharmaceutical Co., Ltd.9 ingredients in the directory
Shandong Zhongxing Food Technology Co., Ltd.8 ingredients in the directory- Zhejiang Ruibang Laboratories4 ingredients in the directory
Zhejiang Tianyi Food Additives Co., Ltd.10 ingredients in the directory
Zhengzhou Ruipu Biological Engineering Co., Ltd.7 ingredients in the directory
Company names and logos are the property of the manufacturers themselves. They are listed here because our own directory records them as producing this ingredient. A listing is not an endorsement by them, and we do not represent them or speak on their behalf.
How We Help Source Zinc Gluconate
Direct Factory Sourcing
We run the whole process: selecting the manufacturer from the top Chinese food ingredient producers, negotiating the price, verifying quality, and coordinating the logistics. You deal with us instead of with several factories at once.
Original Packaging and Documents from the Manufacturer
The manufacturer sends your Zinc Gluconate out of its own factory in the original packing, through to your destination port. The COA, COO, MSDS, TDS and any certifications reach you from the manufacturer as well.
Free Samples and Lead Time
We send 100 to 500 g free for your own laboratory to test and you cover only the courier, usually within 2 to 3 working days. ETD is usually within 7 to 15 days once the order is confirmed, and we check that date against the factory's own manufacturing schedule before we give it to you.
Combined Shipment
We can load Zinc Gluconate together with other ingredients such as Sodium Acetate, Calcium Citrate and Sodium Lactate into one 20' FCL. If your quantity is small, we can also ship LCL.
Regulatory Status
Zinc Gluconate carries broad regulatory approval as a nutrient source.
In the United States it is GRAS for use as a nutrient under 21 CFR 182.8988. The FDA OTC drug framework regulates the cold-lozenge category, with zinc gluconate as a permitted active.
The European Union authorises Zinc Gluconate as a source of zinc in food supplements under Annex II of Directive 2002/46/EC, in foods for general fortification under Regulation (EC) No 1925/2006, and in foods for specific groups under Regulation (EU) No 609/2013.
JECFA evaluated zinc gluconate under the general zinc compound assessment and considers it an acceptable nutrient source.
Pharmacopoeial monographs exist in the United States Pharmacopeia (USP), the European Pharmacopoeia (Ph. Eur.), and the British Pharmacopoeia (BP). Halal and Kosher certifications are widely available.
Manufacturing Process
Industrial production of Zinc Gluconate follows a straightforward acid-base reaction.
D-Gluconic acid, manufactured by the controlled aerobic fermentation of glucose with Aspergillus niger, is the primary raw material. The fermentation broth is filtered, decolorised, and concentrated into a gluconic acid solution or recovered as glucono-delta-lactone.
The gluconic acid solution is reacted with zinc oxide, zinc carbonate, or freshly precipitated zinc hydroxide. The reaction proceeds at 50 to 80 degrees Celsius with mild agitation until pH stabilises at neutral. Excess zinc source is filtered off.
The resulting Zinc Gluconate solution is treated with activated carbon, polish-filtered, and crystallised by cooling or by anti-solvent precipitation with ethanol. The wet cake is washed, dried under vacuum, and milled to the target particle size.
Lead-free zinc oxide is used throughout to meet pharmacopoeial heavy-metal limits.





